Comparative analysis of thyroid diseases incidence in prepubertal children of Kaluga oblast, exposed to iodine-131 in utero and resided in areas with different level of radioactive contamination after the Chernobyl accident

«Radiation and Risk», 2012, vol. 21, no. 4, pp.31-41

Authors

Gorobets V.F. – Lead. Researcher, C. Sc., Med.,.Medical Radiological Research Center of the Russian Ministry of Health, Obninsk.
Contacts: 4 Korolyov str., Obninsk, Kaluga region, Russia, 249036. Tel.: (48439) 9-30-11; e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. .

Abstract

Incidence of non-cancer thyroid diseases among prepubertal children exposed to radiation from Chernobyl in utero and resided in Zhizdra, Ulyanovo and Khvastovichi rayons of Kaluga oblast with different level of radioactive contamination was studied. It was shown that the rate of thyroid diseases incidence depended on natural iodine insufficiency in the areas of residence and radioiodine dose. The relative contribution of each of these factors can be estimated by difference between the incidence rate in exposed and unexposed children of the same age and the same area of residence.

Key words
Сhildren, in utero exposure to radiation, pollution of territories by iodine-131 and caesium-137, iodine supplementation, thyroid diseases incidence.

References

1. Album A., Norell S. Introduction to modern epidemiology. Trans. with English. Tallinn: Institute of Experimental and clinicalal medicine (Estonia); The Danish Anti-Cancer Society, 1996. 122 p.

2. Biglhol R., Bonita R., Kjelstrem T. Fundamentals of Epidemiology. Trans. with English. Geneva: WHO, 1994. 259 p.

3. Bobovnikova Ts. I., Morshina T.N., Matveenko E.G. etc. Features of the microelement composition of drinking water and food in the southwestern regions of the Kaluga region contaminated with radionuclides after the Chernobyl accident. Chernobyl's legacy (15 years later): Proceedings of the Scientific-practical Conference Conf. Kaluga, Obninsk, 2001. Issue. 3. PP. 193-199.

4. Gorobets V.F. Dependence of incidence rates of non-oncological thyroid gland diseases in the postnatal period in children from the Kaluga region from the gestational age at which their intrauterine irradiation occurred due to the incorporation of technogenic iodine-131. Radiation and Risk, 2011. Vol. 20, No. 1. PP. 24-33.

5. Data on radioactive contamination of the territory of the Russian Federation by cesium-137, strontium-90, plutonium-239, 240: Kaluga region. Radiation and risk, 1993. Issue. 3. Appendix 1. PP. 21-25.

6. Data on the reconstruction of specific surface contamination with the iodine-131 isotope of the territory of the Russian Federation as a result of the accident at the Chernobyl nuclear power plant: Kaluga Region. Radiation and Risk, 1993. Issue. 3. Annex 1. PP. 94-101.

7. Evidence of endocrinology. Ed. P. Camacho, H. Gariba, G. Sizmora. Trans. from English. 2nd ed. Moscow: GEOTAR-Media, 2009. 640 p.

8. Ivanov V.K., Tsyb A.F. Medical radiological consequences of Chernobyl for the population of Russia: assessment of radiation risks. Moscow: Medicine, 2002. 392 p.

9. Izrael Yu.A., Zhukova O.M., Ishmennik E.V., Manzon D.A. Forecast mapping of radioactive contamination of territories affected by the Chernobyl disaster. International conference "Chernobyl: experience of international cooperation in the aftermath of the accident", Russia, Moscow-Obninsk, November 23-25, 2011. Theses of reports. Obninsk, 2011. PP. 98-100.

10. Korobova E.M., Anoshko Ya.I., Kesminiene A. et al. Spatially differentiated assessment of the contribution of natural geochemical background of iodine to the risk of thyroid cancer after the Chernobyl accident. Ibidem. PP. 95-97.

11. Mahonko K.P., Kozlova E.G., Volokitin A.A. Dynamics of accumulation of radioiodine on soil and reconstruction of doses from its radiation in the territory contaminated after the Chernobyl accident. Radiation and Risk, 1996. Issue. 7. PP. 140-191.

12. Parshkov E.M., Sokolov V.A., Proshin A.D. Thyroid cancer in children and adults in the Bryansk region after the Chernobyl accident. Vopr. oncol. 2004. Vol. 50, No. 5. PP. 533-539.

13. Pitkevich V.A., Shershakov V.M., Duba V.V. et al. Reconstruction of radionuclide composition of deposition in the territory of Russia as a result of the Chernobyl accident. Radiation and Risk, 1993. Issue. 3. PP. 62-93.

14. Average doses of thyroid gland exposure to people of different ages who lived in 1986 in the settlements of the Bryansk, Tula, Orel and Kaluga regions contaminated with radionuclides as a result of the Chernobyl accident: a handbook. Ed. M.I. Balonova, I.A. Zvonovoy. M .: Ministry of Health of Russia, 2002. Radiation and Risk, 2002. Special Issue. PP. 3-94.

15. Indicators for assessing iodine deficiency disorders and their control through salt iodization: Document WHO/NUT/94.6. Geneva: WHO, 1994. 56 p.

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