Brachytherapy of intraepithelial vaginal cancer (clinical case)

«Radiation and Risk», 2019, vol. 28, No. 4, pp.65-72

DOI: 10.21870/0131-3878-2019-28-4-65-72

Authors

Kulieva G.Z. – Researcher. Contacts: 4 Korolyov str., Obninsk, Kaluga region, Russia, 249035. Tel.: +79533236245; e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. .
Sidorin A.V. – Physician
Verbynskaya N.I. – Physician
Rykova E.V. – Physician
Mozerov S.A. – Senior Researcher
Krikunova L.I. – Head of Dep., MD, Prof.

A. Tsyb MRRC, Obninsk.

Abstract

We present the clinical case of application of high-dose rate ¹⁹²Ir brachytherapy for intraepithelial vaginal cancer using HDR Gammamed afterloder system. The decision to use HDR brachytherapy for vaginal neoplasia was made by consensus of participants of multidisciplinary meeting following the strong analysis of the history of previous diseases, the presence of human papilloma-virus of high carcinogenic risk, results of current examinations, the patient’s age. The treatment plan was developed using the integral dose-volume histogram in accordance with the recommendations of the European Gynecological GEC-ESTRO Working Group. Treatment planning allowed choosing the most appropriate dose distribution, not exceeding the prescribed dose and the optimal target coverage. Due to dose planning it became possible to develop individually tailored treatment program for each patient and improve patient’s quality of life. Effectiveness of treatment of vaginal cancer depends primarily on the extent of the tumor process.

Key words
vaginal cancer, cervical cancer, radiotherapy, HDR ¹⁹²Ir brachytherapy, isodose contour, planning, optimization, human papillomavirus, cervical dysplasia, risk organs, contouring.

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Full-text article (in Russian)