Results of radiation therapy for invasive cervical cancer. Review of Russian literature

«Radiation and Risk», 2023, vol. 32, No. 3, pp.122-133

DOI: 10.21870/0131-3878-2023-32-3-122-133

Authors

Solodkiy V.A. – Director, MD, Prof., Academician of RAS
Panshin G.A. – Chief Researcher, MD, Prof.
Titova V.A. – Chief Researcher, MD, Prof.
Kondrashov A.A. – Medical Resident. RSCRR. Contacts: 86, Profsoyuznaya str., Moscow, Russia, 117997. Tel.: + 7 916 338-37-74; e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. .
Russian Scientific Center of Roentgenoradiology, Moscow

Abstract

Over the past decades, the healthcare system in oncology has undergone significant changes associated with the introduction of information and digital technologies, new diagnostic and treatment algorithms based on visually controlled and fundamentally new technologies of surgical, radiation and drug treatment. These changes also affected socially significant oncological diseases, including cervical cancer (cervical cancer). However, it has not yet been completely possible to adequately solve the problem of diagnosing breast cancer within the 0-I stage of the disease and maintain the priorities of "monotherapy" (organ-preserving options for surgical or radiation treatment). At the same time, the treatment of locally advanced cervical cancer (International Federation of Gynecology and Obstetrics (FIGO) 2009/2018 – stages IB2-IVA/IB3-IVA) has not undergone major changes for almost 80 years and, at the same time, only radiation therapy was considered the standard of treatment for this spread of the tumor process. It should be emphasized that currently the development and implementation of increasingly expensive multicomponent treatment programs for such patients is ongoing, aimed, among other things, at achieving fairly satisfactory results, both in patients' survival and in their quality of life.

Key words
oncology, locally advanced cervical cancer, external beam radiation therapy, brachytherapy, combined radiation therapy, evolution of radiation therapy technologies, overall survival, recurrence free survival, prognostic factors, practical healthcare.

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